2 The Early Years: From Kitchen Microwaves to Multimode Reactors 2.1 Hungary, Rajender S. This also allows a more or less chronological and logical discussion of our research. Upon reflecting on the many different turns our research in microwave chemistry has taken over the years I thought it would be most appropriate to divide this article into different sections based on the type of reactor technology that was used at the time. In order not to disrupt the flow of the manuscript too much many of my personal comments have been placed in the reference section and technical jargon is kept to a minimum so the manuscript can be easily followed by the non-expert reader.
As with most Personal Accounts of this nature, the contributions of other scientists in the field will only be mentioned where this is needed to understand the context of our own work. This somewhat nostalgic journey puts a strong emphasis on why things happened the way they did, focusing more on a political “behind the scenes” perspective, and hopefully will be of interest and an entertaining read for the many “microwave chemists” that were active during that time period. The present article is therefore not a standard scientific review but rather a very Personal Account that describes how my research group got involved in specific research topics within the general area of microwave chemistry over a time period of roughly two decades.
This was perhaps motivated, at least in part, by the fact that one of my postdoc advisors, Albert Padwa, had written an inspirational Perspectives Article for The Journal of Organic Chemistry in 2009, where he most elegantly reflected on how and why his own research interests had progressed and changed quite significantly during the span of close to 50 years of research in organic synthesis. On second thoughts I found the opportunity to reflect on “my twenty years” in the field of microwave chemistry quite appealing and I ultimately accepted the invitation. Since my research activities have shifted away from microwave chemistry some time ago, my first instinct was to decline.
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Personal Chemistry was formed as Labwell AB in 1997, and has raised $14 million in two previous funding rounds.When I received the invitation from the Editors of The Chemical Record to contribute a Personal Account to an upcoming special issue on microwave chemistry I was initially uncertain how to react. In June, the company was forced to pull a $50 million listing on the Stockholm Exchange due to a misunderstanding over patents. ¿Personal Chemistry AB, of Uppsala, Sweden, has raised Krona 178 million (US$18.8 million) in a private placing whose proceeds accelerate the commercialization of Coherent Synthesis, a laboratory bench system for rapid chemical synthesis using microwaves. The three drugs, sold mainly to hospitals, have a combined turnover of #3 million in UK and Ireland. CeNeS is paying #10 million (US$14.1 million) in cash to Glaxo Wellcome plc, of London, for Diconal and Cyclimorph, both analgesics, and Valoid, for countering nausea caused by opioid analgesics. ¿ CeNeS Pharmaceuticals plc, of Cambridge, England, has acquired UK and Ireland rights to three drugs that it says will form the first stage of a pharmaceutical business that will help fund the company's central nervous system and pain control drug development programs.
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